Fauna parasitária e relação parasito-hospedeiro de tambaquis criados na região do Baixo São Francisco, nordeste do Brasil / Parasitic fauna and parasite-host relationship of tambaqui reared in São Francisco river basin, Brazilian northeast

Este trabalho teve como objetivo avaliar a fauna parasitária de tambaquis na região do Baixo São Francisco-AL/SE-Brasil e correlacionar os índices de prevalência e intensidade média com fatores bióticos e abióticos. Foram coletados 252 espécimes para análise parasitológica de 10 pisciculturas. Os parasitos foram contabilizados, identificados, e determinaram-se os índices de prevalência e intensidade média, que foram correlacionados com fatores bióticos e abióticos. Dos peixes coletados, 65,5% estavam parasitados por pelo menos um táxon. Foram encontrados 10 táxons: Monogeneas, Ichthyophthirius multifiliis, tricodinídeos, Piscinoodinium pillulare, Ichthyobodo sp., Dolops carvalhoi, Lernaea cyprinacea, Procamallanus (Spirocamallanus) inopinatus, Henneguya sp. e Myxobolus sp. As maiores prevalências foram encontradas para Monogeneas (49,2%) e Myxobolus sp. (31,5%). Correlações negativas entre prevalência e fatores bióticos (peso e comprimento) foram observadas para Monogeneas (r2= -0,49; r2= -0,43), Myxobolus sp. (r²= -0,46; r²= -0,39) e Henneguya sp. (r²= -0,41; r²= -0,39). O fator abiótico temperatura apresentou correlação negativa com as prevalências de Lernaea cyprinacea (r= -0,39) e tricodinídeos (r= -0,33), enquanto a condutividade elétrica apresentou correlação positiva (r= 0,40) com a prevalência de tricodinídeos. Conclui-se que a fauna parasitária dos tambaquis cultivados na região do Baixo São Francisco é diversificada e com a carga parasitária dependente da qualidade de água e do estágio de desenvolvimento dos peixes.(AU)

This study investigated the parasitic fauna of tambaquis reared in lower Sao Francisco region-Al/SE-Brazil correlating parasitic indices to abiotic and biotic factors. A total of 252 specimens of tambaqui were collected in ten fish farms for parasitological analysis. The parasites were counted, identified and the parasitological indices were determined and correlated to biotic and abiotic factors. Of all collected fish, 65,5 % were parasitized by at least one taxon. Ten taxa were found: Monogeneans, Ichthyophthirius multifiliis, trichodinids Piscinoodinium pillulare, Ichthyobodo sp, Dolops carvalhoi, Lernaea cyprinacea, Procamallanus (Spirocamallanus) inopinatus, Henneguya sp. and Myxobolus sp. The higher prevalences were found to monogeneans (49.2%) and Myxobolus sp. (31.5%). Negative correlation of prevalence and biotic factor (weight and length) were observed to monogeneans (r 2 = -0.49, r 2 = -0.43), Myxobolus sp (r²= -0.46; r²= -0.39) and Henneguya sp (r²= -0.41; r²= -0.39). Abiotic factor of temperature presented a negative correlation to prevalence of Lernaea cyprinacea and trichodinids (r= -0.39 e r= -0.33, respectively) and the electric conductivity presented positive correlation to trichodinids (r= 0.40). It was concluded that parasitic fauna of tambaquis cultured in Lower São Francisco region is diversified and the parasitic load dependent on water parameters and fish growth.(AU)

Tumores neuroendocrinos de origen pulmonar: reporte de un caso / Neuroendocrine tumors of lung’s origin, a case report

Introduction or case story: Young female patient (24 years-old), without known morbid precedents. She comes for a ten-days period of symptoms characterized by fever of up to 38.5 °C and a dyspnoea grade III. Physical exam showed decreased vesicular murmur on the right pulmonary base with dullness and positive vocal vibrations. Exams: Thorax X-ray: Atelectasis condensation on the right pulmonary base. CT chest scan without contrast: Nodule located in an intermediate bronchus which generates atelectasis in the basal bronchi. Fibro-bronchoscopy (FOB): A tumour-like injury blocking 100% of the right intermediate bronchus’ duct. Biopsy: Pulmonary tissue with haemorrhagic areas, granular tissue with small cellular clusters of lobular disposal and glandular shape with eccentric central nuclei cells, with homogenous chromatin and without atypical mitosis. Immunohistochemistry: Intensely positive cells to synaptophysin and CD56. Diagnosis: Neuroendocrine Typical Carcinoid Tumor. Comments: The patient evolves without progression of dyspnoea, she is waiting for a surgical resolution of tumour at National Institute of Thorax.

Introducción o historia del caso: Mujer joven de 24 años de edad, sin antecedentes mórbidos, acudió por cuadro de 10 días de evolución, de fiebre de hasta 38,5 °C y disnea grado III. Al examen físico destacó a nivel pulmonar: murmullo pulmonar disminuido en base pulmonar derecha, matidez de la misma zona y vibraciones vocales positivas. Exámenes: Radiografía de Tórax: Condensación atelectásica en base pulmonar derecha. TAC de Tórax sin contraste: Imagen nodular a nivel de bronquio intermedio, que genera atelectasia en bronquios basales. Fibrobroncoscopía (FBC): Lesión tumoral que ocluye el 100% del lumen para bronquio intermedio derecho. Biopsia: Tejido pulmonar con áreas de hemorragia, tejido granulatorio y tumor con acúmulos celulares de disposición lobular y glanduliforme, con núcleos centrales excéntricos, cromatina homogénea, sin atipias. Inmunohistoquímica: Células intensamente positivas para sinaptofisina, y CD-56. Diagnóstico: Tumor Neuroendocrino Carcinoide típico Comentarios: Paciente evoluciona sin progresión de su disnea, esperando resolución quirúrgica del tumor en Instituto Nacional del Tórax.

Performance of different biofilters in a recirculating system for rainbow trout farming / Desempeño de diferentes biofiltros en un sistema de recirculación para cultivo de trucha arcoiris

ABSTRACT Objective. To evaluate the performance of different biofilters in a recirculating aquaculture system (RAS) for trout farming. Materials and methods. It was used a 1m3 plastic tank for fries farming; fabric bags to solids retention; a submersible pump; a constant water level and flow distribution box; six up flow biofilters in 3" PVC tube; sand of D10=0.45mm as carrier. The reactors were operated at local temperature and with hydraulic retention time (HRT) of 11 min, the biofilters were inoculated in the next way: R1-Control: RAS water; R2-Fish culture farm sludges; R3- Water from aerated lagoon of Antanas landfill (AL); R4-Aquarium sediments; R5- Aerated lagoon of AL sludges; R6-Sludges from sulfidogenic reactor of AL. The weight gain (WG) and the food conversion (FC) were evaluated, some physic-chemical parameters were monitored and the nitrogen and suspended solids removal efficiency were evaluated. Results. The WG of the cultured animals was 1.58 g/d and the FC was 1.41. There were no differences for ammonium and nitrite removal between the reactors; the average removal efficiencies were: ammonium 4.78%, nitrite 27.2%, nitrate 32.3%, suspended solids 37.5%; R4 and R5 reactors presented the best performance on nitrate removal, with average efficiencies of 47.4% and 42.8%. R3 presented the best SS removal with an average of 58.2%. Conclusions. The RAS water treatment system guaranteed appropriated liquid quality conditions for trout farming; the most efficient reactor for removal of the different forms of nitrogen was the inoculated with the aerated lagoon of AL sludges.

RESUMEN Objetivo. Evaluar el desempeño de diferentes biofiltros en un sistema de recirculación (SRA) para cultivo de trucha arcoiris. Materiales y métodos. Se utilizó: un tanque de 1m3 para cultivo de alevines, bolsas de lienzo para retención de sólidos, bomba sumergible, caja de nivel constante y distribución de flujo, seis biofiltros en tubo de PVC de 3", arena con D10=0.45mm como medio soporte. Los biofiltros se operaron a temperatura ambiente y con tiempo de retención hidráulica (TRH) de 11 min, se inocularon así: R1-Control: Aguas del SRA; R2-Lodos estación piscícola; R3-Agua Laguna aireada relleno sanitario Antanas (RSA); R4-Sedimentos acuarios; R5-Lodos laguna aireada RSA; R6-Lodos reactor sulfidogénico RSA. Se evaluó la ganancia de peso (GP) y la conversión alimenticia (CA), se monitorearon parámetros físico-químicos y se evaluó la eficiencia de remoción de nitrógeno y sólidos suspendidos. Resultados. La GP de los animales fue de 1.58 g/d y la CA de 1.41. No hubo diferencias para remoción de amonio ni nitritos entre reactores; las eficiencias medias de remoción fueron: amonio 4.78%, nitrito 27.2%, nitrato 32.3%, sólidos suspendidos 37.5%. Los reactores R4 y R5 presentaron mejor remoción de nitratos, con eficiencias medias de 47.4% y 42.8%. El R3 reportó la mejor remoción de SS con promedio del 58.2%. Conclusiones. El sistema de tratamiento del agua en el SRA garantizó condiciones de calidad del líquido, apropiadas para el cultivo de la trucha; el reactor más eficiente para la remoción de las formas de nitrógeno evaluadas fue el inoculado con lodos de la laguna aireada del RSA.

Successful domino liver transplantation in maple syrup urine disease using a related living donor

Maple syrup urine disease (MSUD) is an autosomal recessive disease associated with high levels of branched-chain amino acids. Children with MSUD can present severe neurological damage, but liver transplantation (LT) allows the patient to resume a normal diet and avoid further neurological damage. The use of living related donors has been controversial because parents are obligatory heterozygotes. We report a case of a 2-year-old child with MSUD who underwent a living donor LT. The donor was the patient's mother, and his liver was then used as a domino graft. The postoperative course was uneventful in all three subjects. DNA analysis performed after the transplantation (sequencing of the coding regions of BCKDHA, BCKDHB, and DBT genes) showed that the MSUD patient was heterozygous for a pathogenic mutation in the BCKDHB gene. This mutation was not found in his mother, who is an obligatory carrier for MSUD according to the family history and, as expected, presented both normal clinical phenotype and levels of branched-chain amino acids. In conclusion, our data suggest that the use of a related donor in LT for MSUD was effective, and the liver of the MSUD patient was successfully used in domino transplantation. Routine donor genotyping may not be feasible, because the test is not widely available, and, most importantly, the disease is associated with both the presence of allelic and locus heterogeneity. Further studies with this population of patients are required to expand the use of related donors in MSUD.

Esofagitis inducida por doxiciclina: reporte de un caso clínico / Doxycycline-induced esophagitis: a case report

La esofagitis asociada a ingesta de medicamentos es una complicación poco frecuente. Su real incidencia es subestimada debido a que es una patología autolimitada y no siempre diagnosticada. Presentamos el caso de una mujer de 17 años que consulta por dolor a nivel de tercio medio del tórax que aparece después de una semana de consumo de doxiciclina. El diagnóstico se certificó mediante endoscopia, se indicó la suspensión del antibiótico y la administración de ranitidina por 7días. La paciente se hizo asintomática al tercer día de suspensión del fármaco y la endoscopia de control realizada 45 días después fue normal.

Esophagitis due to pill ingestion is an uncommon condition. The real incidence is underestimated because it is usually a self limited disorder and the diagnosis is not always established. We report a case of a 17 years old female presenting with an acute onset of pain in the middle chest one week after consumption of doxycycline. Endoscopy confirmed the diagnosis. The antibiotic was withdrawned and ranitidine was administered for seven days. The patient was asymptomatic at the third day of treatment and a control endoscopy at day 45 was normal.

Alimentary canal and reproductive tract of Hypothenemus hampei (Ferrari) (Coleoptera: Curculionidae, Scolytinae)

The alimentary canal and the reproductive tract of males and females of Hypothenemus hampei Ferrari are described. The alimentary canal of H. hampei showed the crop with several spine-like structures and the midgut with few gastric caeca. We evidenced for the first time that adult females need to feed on coffee in order to produce viable eggs before and during oviposition period. The presence of air bubbles inside the anterior midgut may be due to starvation rather than the response of the environment during flying as previously reported. Two ovaries and the same structures and arrangements common to individuals of the Curculionidae beetles composed the female reproductive system. The male reproductive tract showed a significant difference with respect to other Curculionidae and even other Scolytinae species as it showed a sclerotized aedeagus with several pore-like structures in the terminal portion where sperm is released during mating.

El estudio morfológico del tracto digestivo y el sistema reproductor de machos y hembras de Hypothenemus hampei Ferrari se describe a continuación. El tracto digestivo presenta un arreglo típico descrito para otros insectos. Ahora las diferencias morfológicas se encontraron en el buche del estomodeo, en donde se observaron estructuras espinosas y en el mesenteron se observo un número reducido de ciegos gástricos. Se evidenció por primera vez el comportamiento de la alimentación de las hembras de H. hampei, que requiere aparentemente de la ingesta del endosperma del café para poder producir huevos viables durante la oviposición. La presencia de burbujas de aire al interior del ventrículo anterior se cree que puede ser debido al hambre, más que a la respuesta al medio ambiente durante el vuelo como lo indicaban anteriores observaciones. El sistema reproductor de la hembra presenta dos ovarios y un arreglo estructural común a especímenes de la familia Curculionidae. El sistema reproductor masculino mostró una diferencia significativa con respecto a otros miembros de la familia Curculionidae e incluso a otra especie de la tribu Scolytinae presentando un aedeagus esclerotizado compuesto de varios orificios en la porción terminal, por donde el esperma se expulsa durante el apareamiento.

Evaluación del impacto de una intervención alimentario nutricional en niños chilenos con malnutrición por déficit / Impact evaluation of a nutritional intervention in Chilean children with malnutrition

Background: In the year 2003, the Ministry of Health replaced rice from the Complementary Nutritional National Program destined to malnourished and in risk children, for a product with higher nutritional value ("Mi Sopita"). Objective: Evaluate the effect of this intervention in the nutritional evolution of children under 6 years-old, in risk or suffering malnutrition. Method: Retrospective cohort of 1.576 children registered in the program 6 months earlier in 300 Primary Care establishments. Analysis of the evolution of anthropometric indicators for a period of 6 months, in function of the initial diagnosis and age. Logistic regressions of multiple factors to determine the variables associated to a better nutritional evolution. Results: 80 percent of cases presented nutritional risk and the rest malnutrition. In 6 months, the median value of change in Z score for weight/age was + 0,3 SD (95 percent IC 0,3-0,3), height/age +0,3 SD (0,3-0,4) and weight/height +0,5 SD (0,3-0,6) in children with initial values < -2 SD. The change was approximately 0,1 SD for the group with nutritional risk. Between 44 percent and 69 percent of the children with malnutrition got partially better or normalized their nutritional status according to the different indicators (p < 0,001). The most determinant factor for better evolution was major initial nutritional deficit (OR 4,4 IC 3,2-6,1 p < 0,001 for weight/age). Conclusions: The program has a positive effect in the recovery of malnourished children and it avoids major nutritional deterioration in children at risk.

Antecedentes: El 2003 el Ministerio de Salud introdujo un nuevo alimento de mayor valor nutricional (Mi Sopita) en el Programa Nacional de Alimentación Complementaria de refuerzo destinado a niños en riesgo nutricional y desnutridos. Objetivo: Evaluar el efecto de esta intervención en la evolución de los indicadores antropométricos y estado nutricional de menores de 6 años en riesgo y desnutridos. Material y Método: Cohorte retrospectiva de 1 576 niños ingresados al programa 6 meses atrás en 300 establecimientos de atención primaria. Análisis de la evolución de la relación peso-edad, talla-edad y peso-talla entre el ingreso y los 6 meses, en función del diagnóstico inicial y la edad. Regresiones logísticas multivariadas para determinar los factores asociados a una mejor evolución nutricional. Resultados: El 80 por ciento de la muestra presentaba riesgo nutricional y el resto desnutrición. En 6 meses la mediana de cambio del puntaje Z en niños que ingresaron con valores < - 2 DE fue de + 0,3 DE (95 por ciento IC 0,3-0,3) para peso-edad, + 0,3 DE (0,3-0,4) para talla-edad y +0,5 DE (0,3-0,6) para peso-talla. El cambio fue menor (aproximadamente + 0,1 DE para el grupo en riesgo nutricional. El 44 al 69 por ciento de los niños desnutridos mejoró parcialmente o normalizó su estado nutricional según los diferentes indicadores (p < 0,001). El factor más determinante de una mejor evolución fue un mayor déficit nutricional inicial (OR 4,4 IC 3,2-6,1 p < 0,001, para la relación peso-edad). Conclusiones: El programa tiene un efecto positivo en la recuperación de los niños con desnutrición y evita un mayor deterioro nutricional en los niños en riesgo.

Predictores de coledocolitiasis en población de alto riesgo sometida a pancreatocolangiografía retrógrada endoscópica en el Hospital Arzobispo Loayza / Predicting of choledocholithiasis in population of high risk submissive an endoscopic retrograde cholangiopancreatography in yhe Hospital Arzobispo Loayza

Introducción: La coledocolitiasis es una complicación frecuente de la litiasis vesicular. La pancreatocolangiografía retrógrada endoscópica (PCRE) es el "gold Standard" para su diagnóstico y tratamiento, sin embargo debido a su significativa morbilidad y mortalidad, otros métodos diagnósticos han sido planteados, tales como la colangiografía intraoperatoria (CIO) y la colangioresonancia (CRMN), reservado a la PCRE sólo para fines terapéuticos. Objetivo: Verificar la utilidad de los predoctores de coledocolitiasis descritos en la literatura. Material y Método: Estudio correlacional, observacional, transversal prospectivo que se realizó entre agosto del 2004 y enero del 2005 en el Hospital Arzobispo Loayza. Conocidos criterios clínicos, bioquímicos y ecográficos predictores de coledocolitiasis fueron analizados en 151 pacientes sometidos a PCRE. Usando análisis univariado y multivariado, se identificaron los factores de riesgo para coledocolitiasis, en el total de pacientes del estudio, así como en los pacientes colecistectomizados o no antes de la PCRE. Resultados: El análisis univariado en el total de pacientes encontró que la edad, ictericia, colangitis, biblirrubina directa, amilasa, deshidrogenada láctica (DHL), dilatación del colédoco (>8mm) y coledocolitiasis por ecografía, estuvieron asociados con coledocolitiasis. Cuando se evaluó por separado, el análisis multivariado en los tres grupos se encontró que sólo la dilatación del colédoco por ecografía fue el único predictor de coledocolitiasis en el grupo de pacientes post-operados. Conclusiones: Ningún indicador único es capaz de predecir, con total exactitud, la presencia de coledocolitiasis. Pero los parámetros descritos en la literatura, son de utilidad en nuestro medio.

Introducction: The choledocholithiasis is a frequent complication of gallstone disease. The endoscopic retrograde cholangiopancreatography (ERCP) is suitable for its diagnosis and treatment. That approach has both significative morbility and mortality so others methods of diagnosis have been proposed such as intraoperatorycholangiography (IOC) and magnetic resonance cholangiography (MRC), reserving ERCP only for therapy purpose.OBJETIVES: Verify the utility of choledocholithiasis predictors described in literature MATERIAL AND METHODS: This study is a correlational observational transversal prospective approach. It was performed at the Arzobispo Loayza Hospital from August 2004 to January 2005. Many clinical, biochemical and ecographyc predictorsof choledocholithiasis were analyzed in 151 patient underwent to ERCP. In all people under study and analyzing separately patients underwent to cholecystectomy or not previous to ERCP, it was identified some risk factors for choledocholithiasis by means of both univariate and multivariate analysis.RESULTS: The univariate analysis showed a relationships among age, icterus, cholangytis, direct bilirrubin, amylase, lactic deshidrogenasa, ductal dilatation (minor 8mm) and choledocholithiasis. In all groups, the multivariate analysis determined that ductal dilatation by ecography was the unique predictor for choledocholithiasisin the group of patients postoperated.CONCLUSIONS: None single indicator was able to predict with accuracy thecholedocholithiasis. However, the parameters described in the literature are useful in our country.

Eritrodermia exfoliativa y dermatitis infecciosa en un lactante infectado por el virus linfotrópico humano-I (HTLV-I) / Exfoliative erythroderma and infective dermatitis in an infant infected with human T-lymphotropic virus type I (HTLV I)

We report a HTLV-I positive infant, whose infection was confirmed by polymerase chain reaction. The infant presented with an acute, severe, generalized eczema, exfoliation and severe erythroderma that yielded to an acute proteic malnutrition and frequent staphyloccocal infections, unresponsive to treatment, since the second month of life. Immunodeficiencies from other origin and other causes of erythroderma were ruled out. The histopathology studies and clinical course yielded to the diagnosis of infective dermatitis associated to HTLV-I. A review of the literature is performed.

Se presenta un niño infectado por virus HTLV-I por vía vertical, confirmado por reacción de polimerasa en cadena, quien, a partir del segundo mes de vida, presentó un cuadro de eccema agudo severo generalizado, que llegó a la eritrodermia y exfoliación masiva, provocando una desnutrición proteica aguda e infecciones repetidas por Staphylococcus aureus, de difícil manejo. Se descartaron inmunodeficiencias de otro origen, así como otras causas de eritrodermia. Posteriormente, de acuerdo con la evolución clínica y con las biopsias, se interpretó el cuadro como una dermatitis infecciosa asociada a HTLV-I. Se revisa la literatura en relación a la infección por HTLV-I.

Edema hemorrágico agudo del lactante / Infant acute hemorrhagic edema

El edema hemorrágico agudo del lactante (EHAL) es una variante de vasculitis leucocitoclástica confinada a la piel que se caracteriza por placas purpúricas y edema de las extremidades, en un niño en buenas condiciones generales. Durante una o dos semanas previas al inicio del cuadro se describen infecciones, uso de drogas o inmunizaciones los que gatillarían un proceso inmunológico mediado por inmunocomplejos. Su principal diagnóstico diferencial es el púrpura de Schõnlein-Henoch. Es de evolución benigna y autolimitada. Objetivo: Presentar un caso de EHAL, dando a conocer la enfermedad y entregar herramientas de diagnóstico. Caso clínico: Lactante de 8 meses que presenta edema y lesiones purpúricas extensas en cara y extremidades asociadas un cuadro respiratorio intercurrente. No había compromiso del estado general, los exámenes de laboratorio fueron normales y la biopsia de piel fue compatible con EHAL. Se descartaron los diagnósticos diferenciales más importantes. No se realizó ningún tratamiento específico y el cuadro remitió en forma espontánea sin recurrencias posteriores. Este caso representa el cuadro típico del edema hemorrágico agudo del lactante, el cual es poco frecuente, pero sus manifestaciones cutáneas son muy alarmantes y pueden originar confusión en el diagnóstico.

Prioridades de intervención en alimentación y nutrición en Chile / Food and nutrition intervention priorities in Chile

The demographic and nutritional transition in Chile has been reflected by a high and growing prevalence of obesity and chronic illnesses related to nutrition. In spite of the efforts made, it is not likely that the country will comply with the health objectives proposals for 2010 to reduce obesity and sedentary tendencies. As part of their functions the National Health Food and Nutrition Advisory Council has recently checked and defined the national priorities in this area. In the Council's opinion, the efforts should be oriented to strengthen the nutritional intervention strategy through the vital cycle, to improve the institutional capacity of the country as far as food is concerned, to review and modernized feeding programmes and to develop a strategic alliance with food producing companies, scientific societies, academic groups and consumers. These actions are directed to promote a wider and better offer of healthier food and to regulate publicity. In order to advance in these proposals we need a major investment from public and private resources oriented to promote healthier styles of living, with special emphasis on nutrition and physical activity.

La transición demográfica y nutricional que vive Chile se ha reflejado en una prevalencia alta y creciente de obesidad y enfermedades crónicas vinculadas a la alimentación. A pesar de los esfuerzos realizados es poco probable cumplir con las metas sanitarias propuestas para el 2010 en cuanto a reducir la obesidad y el sedentarismo. Como parte de sus funciones el Consejo Asesor en Nutrición y Alimentación del Ministerio de Salud ha revisado recientemente y definido las prioridades nacionales en este campo. En la opinión del Consejo los esfuerzos debieran orientarse fundamentalmente a fortalecer la estrategia de intervención nutricional a través del ciclo vital, a mejorar la capacidad institucional del país en el ámbito de los alimentos, a revisar y modernizar la gestión de los programas alimentarios y a desarrollar una alianza estratégica con las empresas productoras de alimentos, sociedades científicas, grupos académicos y con los propios consumidores orientada a promover una mayor oferta y consumo de alimentos saludables y a regular la publicidad en este campo. Para avanzar en la meta propuesta se requiere sin duda de una mayor inversión de recursos públicos y privados fundamentalmente orientados a la promoción de estilos de vida saludable, con especial énfasis en alimentación y actividad física.

Evaluación de la aceptabilidad y consumo de un nuevo producto del Programa Nacional de Alimentación complementaria: Mi sopita / Evaluation of acceptability and consumption of a new product from the National Program of Supplementary Nutrition: Mi Sopita

Antecedentes: En Chile, aún el 3,7 por ciento de los niños(as) menores de 6 años presenta déficit nutricional, los que son incorporados a un programa de refuerzo nutricional cuya evaluación permanente ha contribuido a mejorarlo. Objetivo: Evaluar la aceptabilidad y consumo de un nuevo producto (Mi Sopita) y de los principales factores asociados a la frecuencia y cantidad consumida. Material y Método: Estudio de prevalencia en una muestra representativa de 2 885 beneficiarios de 20 Servicios de Salud. Encuesta estructurada a la madre sobre retiro, frecuencia y forma de consumo, aceptabilidad y dilución intrafamiliar. Resultados: 85 por ciento de las familias retiran regularmente el alimento, 60 por ciento de las madres consideran que al niño (a) le gusta, 50 por ciento diluye el producto en la familia. El consumo promedio fue de 4,5 ± 2,1 días semanales, 1,5 ± 0,6 raciones diarias de 39,7 ± 22,0 gramos cada una, sin diferencias significativas por edad o estado nutricional integrado. La variable más determinante para el consumo fue la opinión de la madre sobre la aceptabilidad por el niño (a) y en menor grado la frecuencia de retiro, la dilución intrafamiliar y una relación peso-edad inicial < de 2 DE. Conclusiones: El producto tiene una adecuada aceptabilidad y consumo. La dilución intrafamiliar es menor que para los alimentos tradicionales. Es fundamental reforzar la educación al equipo de salud y la familia para mejorar la valoración social, el consumo y eventualmente el impacto nutricional.

Background: 3.7 percent of Chilean children under 6 years-old present a nutritional deficit and are incorporated into a reinforcement nutritional program with permanent evaluations that have contributed to its improvement. Objective: to evaluate the acceptability and consumption of a new product (Mi Sopita) and the main factors associated to frequency and amount consumed. Method: Prevalence study in a representative sample of 2 885 children from 20 Health Services. Structured survey to the mother about frequency, acceptability and product dilution within the family. Results: 85 percent families regularly get the food, 60 percent mothers consider that the child likes it and 50 percent dilute the product within the family. The average consumption was 4.5 ± 2.1 days weekly, 1.5 ± 0.6 daily rations of 39.7 ± 22.0 g each and no significant differences in age or nutritional status. The most determinant variable for consumption was the mother’s opinion about acceptability by the child and, in a lower degree, the frequency in obtaining the product, the dilution within the family and an initial weigh for age < 2 SD. Conclusions: Mi Sopita has an adequate acceptability and consumption. The dilution of the product within the family is less than the traditional food. It is very important to reinforce education to the health team and family, improve social level, consumption grade and the nutritional impact.

Mastitis granulomatosa idiopática y mastitis de células plasmáticas: experiencia de tres años / Granulomatous mastitis and plasmatic cell mastitis: three-year experience

Se evaluó el manejo de 13 pacientes con mastitis granulomatosa idiopática y mastitis de células plasmáticas, tratadas en el Hospital Félix Bulnes, por un período de tres años. Se estudió la relación con la edad, anticoncepción, embarazo, lactancia y la atopia. Se evaluaron las limitaciones de la mamografía y de la ecotomografía mamaria y el uso de la biopsia trucut. Se compararon los resultados del tratamiento médico y quirúrgico.

Neoplasia trofoblastica gestacional: Hospital Félix Bulnes Cerda, 1992 - 2002 / Gestational trophoblastic neoplasia: Hospital Félix Bulnes Cerda, 1992 - 2002

Objetivo: Analizar los hallazgos clínicos y el seguimiento de los casos de neoplasia trofoblástica gestacional. Material y Métodos: Se revisaron todos los casos de mola hidatidiforme en el Hospital Félix Bulnes Cerda, entre los años 1992 y 2002. Resultados: Se diagnosticaron 79 casos. La edad promedio de las pacientes fue 26,4 años. El diagnóstico de mola hidatidiforme fue sospechado clínicamente en 75,6 por ciento y en 24,4 por ciento fue hallazgo anatomopatológico. Los principales síntomas al ingreso fueron: dolor hipogástrico (75,6 por ciento), náuseas y/o vómitos (32,1 por ciento) y disuria (19,2 por ciento). Entre los signos clínicos destacan sangrado vaginal (83,3 por ciento), altura uterina discordante (25,3 por ciento) y expulsión de vesículas (12,8 por ciento). La ecografía concluyó mola hidatidiforme en 74,4 por ciento y quistes tecaluteínicos en 23,1 por ciento. Los hallazgos de anatomía patológica fueron mola completa (61,5 por ciento), mola parcial (31,2 por ciento) y coriocarcinoma (1,3 por ciento). En el seguimiento, 30,8 por ciento no volvieron a control y 23,1 por ciento tuvieron entre 7 y 12 controles. Conclusión: Los hallazgos de este estudio son similares a los descritos en la literatura.

Genetic parameters of wool colour and skin traits in Corriedale sheep

Clean wool colour (CWC) is an important wool price determinant and has been related to suint characteristics, i.e. sudoriparous and sebaceous gland secretions, such as suint percentage and suint K content. In this work heritability, phenotypic and genetic correlations among wool colour and skin traits were examined. The genetic estimates were assessed by Restricted Maximum Likelihood (REML) procedures using average information algorithm (AIREML) in a Corriedale flock. The traits analysed were wool colour traits (CWC), yellow predictive colour (YPC), and Visual Score; suint traits such as suint percentage and potassium and sodium concentrations in suint, and physiological traits such as potassium and sodium concentrations in the skin, including plasma and red blood cells. The objectives of this study were to assess phenotypic and genetic correlations between wool colour and skin traits, and to find the suitability of these traits as indirect selection criteria for clean wool colour. Suint traits were highly genetically correlated to YPC. Suint K, but not suint percentage, was found to have a high genetic correlation with CWC. Skin K, Visual Score, YPC and suint K were amongst the best indirect selection criteria for clean wool colour. However, selection using these traits was expected to reduce CWC from 52 percent to 49 percent of that estimated under direct selection

Indirect selection criteria against clean wool colour in Corriedale sheep and their effects on wool production traits

The potential of greasy wool colour subjective assessment Visual Colour Score (VCS) and the yellow predictive test (YPC) as indirect selection criteria for reduction of clean wool colour (CWC) in Corriedale sheep was examined. The heritability of these wool colour traits and the wool production traits, greasy (GFW) and clean fleece weights (CFW), and mean fibre diameter (MFD) and the phenotypic and genetic correlations among these traits were estimated from a Corriedale flock using AIREML procedures. A high genetic correlation between YPC and CWC was observed, indicating that YPC could be a suitable indirect selection criterium for CWC. However, direct selection against CWC was predicted to produce faster genetic improvements in CWC than that expected under indirect selection via YPC. Single trait selection based on VCS or YPC were expected to reduce the response in CWC to 51 per cent and 49 per cent of that estimated for direct selection. The positive genetic correlations of CWC, YPC and VCS with CFW and MFD would cause a reduction in both MFD and CFW to result from selection that reduces wool colour. The results showed that the most effective way to genetically improve CWC was through indirect selection to reduce MFD, CFW or GFW, followed by direct selection, but the premiums for CWC in the Corriedale breed may not be sufficient to justify the expected losses in CFW

Características alimentarias de adultos mayores de comunas pobres de la Región Metropolitana / Alimentary features of elders living in poor communities of the Metropolitan Region of Chile

Background: The higher life expectancy of the Chilean population has required a greater concern about health and nutrition of elderly people. Aim: To assess the alimentation of people over 65 years old, living in communities of the Metropolitan Region with high social vulnerability. Material and methods: A random and representative sample of 257 elders living in the poorest communities of Santiago was studied. They were interviewed in their homes about feeding patterns, the alimentation of the day before and their nutritional status. Mean energy and nutrient consumption and their fitting to FAO/WHO energy and National Research Council micronutrient recommendations were calculated. A feeding quality index, that considers the adequacy of consumption of all nutrients, was calculated. Results: Except for bread, median consumption of all groups of foods was below recommendations. Median energy and protein consumption was 1438 Kcal and 53.9 g in men and 1118 Kcal and 37.7 g in women. Adequacy of consumption of all nutrients was low and the intake of energy, protein, calcium, iron and folate was significantly lower in women than in men. The factors associated with feeding quality in these subjects were a last meal of the day before different from supper, more than 15 hours of morning fasting and sex. Conclusions: Alimentation of elders living in poor communities of Santiago is severely deficient. Focalized intervention models to improve this situation should be devised

Patrones alimentarios en adultos que asisten a consultorios de atención primaria en la región metropolitana / Food patterns in adult outpatients at metropolitan region

A non-randomly selected group of 859 adults (410 men) from 120 health care centers of the National Health System (oct. 1995) was studied. Food intake was assessed by 24 hours recall applied by well-trained standarized nutritionists. Both frequency and food and nutrients intake were calculated. The mean age was 35.8ñ10.6 years old. Median energy, protein and fat intake in male were 2324 kcal, 84g y 70g, respectively. For women, medians intake were: 1668 kcal, 59g and 53g respectively. From the total sample 72 percent, 53 percent y 71 percent reported consumption of less than 2 servings of milk product, vegetables and fruits. Likewise 42, 36 and 22 percent of subjects had calcium, vitamin A and C intake below than 50 percent of the corresponding recommended dietary allowances (RDA). On the other hand 24 percent of the sample had daily salt consumption higher than 5g, 37 percent had energy intake derived from fat higher than 30 percent of total calories and 15 percent had more than 10 percent of the energy supplied by sugar. A significant part of the adult population had inadequate patterns of food intake which confirms the need to promote a healthier diet